Church of Christ

The Cathedral of St. Mary of the Annunciation serves as a central place of worship and community engagement, embodying the mission of fostering faith and community.

Westminster Presbyterian Church in Cape Girardeau, MO is part of the Presbyterian Church (USA) and focuses on worship and community service, offering programs like a clothing closet and a community garden.

St. Mark Lutheran Church aims to celebrate the Word of God and respond to human need, providing a welcoming sanctuary for a diverse community.

First Pentecostal Church is a warm and loving church that centers its preaching and teaching on the Word of God, providing ministries for all ages.

First General Baptist Church is dedicated to impacting Cape Girardeau and the surrounding area for Jesus Christ and the Kingdom, having been an influence in the community since its founding in 1927.