St. Mark Lutheran Church

The Cathedral of St. Mary of the Annunciation serves as a central place of worship and community engagement, embodying the mission of fostering faith and community.

Westminster Presbyterian Church in Cape Girardeau, MO is part of the Presbyterian Church (USA) and focuses on worship and community service, offering programs like a clothing closet and a community garden.

First Pentecostal Church is a warm and loving church that centers its preaching and teaching on the Word of God, providing ministries for all ages.

First General Baptist Church is dedicated to impacting Cape Girardeau and the surrounding area for Jesus Christ and the Kingdom, having been an influence in the community since its founding in 1927.

Old St. Vincent's Church is a historic Catholic church located in downtown Cape Girardeau, Missouri near the Mississippi riverfront, notable for its rare English Gothic Revival Renaissance architecture. The church serves as both an active parish and a significant historical and spiritual landmark in Missouri's Catholic tradition.

St Mark Hope and Peace Lutheran Church ELCA is a Reconciling in Christ congregation committed to inclusivity, welcoming people of all sexualities and gender identities, and striving to put faith into practice through community service and love.

Messiah Lutheran Church is a community-focused church that aims to share life through the love of Christ, serving the neighborhood and the diverse community around them.

Bethlehem Lutheran Church is a proud member of the Lutheran Church—Missouri Synod (LCMS), dedicated to providing God-honoring worship and ensuring a connection to faith and community through various ministries.

The Chapel of St. Timothy and St. Titus serves as a central place of worship at Concordia Seminary, where students and the community come together to hear the Lord's promises and participate in worship.

Campus Lutheran Church lives and shares the transforming love of Christ by reaching upward, outward, and inward.