First Presbyterian Church

Westminster Presbyterian Church in Cape Girardeau, MO is part of the Presbyterian Church (USA) and focuses on worship and community service, offering programs like a clothing closet and a community garden.

St. Mark Lutheran Church aims to celebrate the Word of God and respond to human need, providing a welcoming sanctuary for a diverse community.

First Pentecostal Church is a warm and loving church that centers its preaching and teaching on the Word of God, providing ministries for all ages.

First General Baptist Church is dedicated to impacting Cape Girardeau and the surrounding area for Jesus Christ and the Kingdom, having been an influence in the community since its founding in 1927.

Old St. Vincent's Church is a historic Catholic church located in downtown Cape Girardeau, Missouri near the Mississippi riverfront, notable for its rare English Gothic Revival Renaissance architecture. The church serves as both an active parish and a significant historical and spiritual landmark in Missouri's Catholic tradition.