First Church of Christ Scientist

Edwards Church of Northampton is an Open and Affirming United Church of Christ congregation situated at the crossroads of State, Main, and South Streets in downtown Northampton. The church combines spiritual worship with worldly service, hosting a soup kitchen, mindfulness center, Buddhist sangha, and parents' center alongside traditional worship.

College Church is a diverse, interdenominational Protestant church in Northampton, seeking to 'Know Christ and Make Him Known' through biblical preaching and local outreach.